Laboratory Animal models are very essential for measuring in-vitro and in-vivo test in animal models of diabetes and other diseases, alternative methods have launched like cell culture and spectroscopies and microscope levels. What are latest models including most commonly employed ones.
Dear colleague,
As I see it, the classic has its charms. Drug-induced diabetes, such as in streptozotocin models, are not only prevalent in the literature, but also current. I found these interesting reviews on the topic:
https://www.ncbi.nlm.nih.gov/pubmed/15787657
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417415/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418001/
https://www.nature.com/articles/ni0209-129
And, of course, you can aways see what the companies are producing:
http://www.criver.com/find-a-model?therapeutic_area=Diabetes&loc=BR
Sincerely,
Hércules Freitas
Rodent models are the only choice in case of diabetes either you use mice or Rabbits Alloxon and Streptozotocin are the two agents commonly used.
Recommend this:
Article The use of animal models in diabetes research
Hi Abdul:
In order to choose the latest and promising model of the diabetes, I recommend you few publications on the coordinated expression of several genes of the Mup locus (Chr 4) and the development of the disease during mice ontogenesis:
doi: 10.1016/S0083-6729(10)83006-7
doi: 10.1074/jbc.M109.001107
doi: 10.1074/jbc.M900754200
Best regards
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