is it new strain of P.vivax?
is it related to liver maturity?
is it related to failure of parents to observe the initial symptoms?
or is it due to other factors?
It may be related to immune development. Adults are more immunocompetent than the children. Also adults have build enough antibodies against the infection because of their exposure to the infection.
yeah , you added an important factor which is the variation between young children and adult immunity.
thanks dear.
While P.vivax does not produce the clinical features of severe P.falciparum malaria related to the sequestration of infected red blood cells (such as coma), it can still provoke a high fever. A young child with a high fever (of any cause) is more likely to have febrile convulsions than an adult with a high fever.
some studies discussed about mutation in certain strains of P.vivax
Children are more sensitive than adults and shows the severe symptoms of any illness which is due to the complicated or immature immune system than in adults.. .
P. vivax has been neglected and mistakenly considered as “Benign” but there are few evidences in the past decade from studies in different countries that P. vivax is able to cause severe disease... which may be due to its several biological differences like the development of the dormant stage in the liver (hypnozoites) causing relapse and greater transmission potential of P. vivax at low parasite densities and it is the most common geographically widespread species..
Basically it is due to the difference in the immunity of children and adults
It is well known as "febrile convulsions" in pediatric age group. Nothing to do with P. vivax to the best of my knowledge.
Children are more sensitive than adults and shows the severe symptoms of any illness which is due to the complicated or immature immune system than in adults.. .
Sure, immunity have a role , but we should now the possible mechanism , that induce the severe symptoms among infected children.
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