What are the pretrained-language-model that is obviously better than BERT and RoBERTa?

19 January 2021 602 2 View

Can I design an aptamer that can sense microbial activity?

I am trying to design a boron nitride based biosensor that can sense the abnormality of microbial activities on fish skin. I am very curious that is it possible to have such an aptamer that can...

23 September 2020 6,352 4 View

Can I build a stable cell line for CO-IP?

I want to know two protein interactions via CO-IP, and one of the proteins has several different mutations. I need to transfect all these mutations into HEK293T cells for doing Co-IP every time,...

03 September 2020 342 3 View

Based on transformer, how to improve the text generation results?

If I do not pretrain the text generation model like BART, how to improve the result based on transformer like tensor2tensor? What are the improvement ideas for transformer in text generation task?

18 August 2020 7,265 3 View

Are there any deep models that are better than BERT-CRF in NER task?

Named entity recognition (NER) is task that mark tags of the input text sequence. BERT-CRF is a good NER model. I want to find a better NER model. Or I want to improve the BERT-CRF model. What...

18 August 2020 7,070 2 View

What are the effects of gender of performer on animal?

I remember a paper studied the effects of gender of handler on animal (mouse?) showing that male handler has more negative effects on animal (for example, causing animal anxious) compared to...

05 August 2020 4,131 1 View

Question of pretraining text-generation task, it seems that pretraining is not work for a small model?

My task is to generate keywords from sentences. I pretrain a text-generation model. I mask the sentences' tokens and predict the whole sentences' tokens. Pretraining batch_size = 8 and step =...

28 July 2020 5,675 1 View

How to tackle endogenous problems with "truncated" data structure?

When I want to estimate educational return, I run a regression like: ln(wage)=beta1+beta2*education+other control variables+u In order to tackle the endogenous problems induced by potential...

21 June 2020 2,244 1 View

What is the principle of Unsupervised Data Augmentation (UDA)? Why does UDA work?

UDA(https://github.com/google-research/uda) could achieve good accuracy by only 20 training data on text classification. But I find it is hard to reproduce the result on my own dataset. So I...

05 June 2020 1,486 2 View

What are the simplest methods for the label noise problem?

If I have enough low quality data from unsupervised methods or rule-based methods. Do you think removing the wrong data predicted by trained model is a simple but effective method?

02 June 2020 4,078 3 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

What kind of fluid could I use for a pitfall trap that also does not invalidate molecular testing?

Hi, I want to start testing pitfall trap to obtain ants samples, but I need to conduct molecular analysis on those insects. So, what kind of fluid can I use? Ethanol expires too early and I need...

03 March 2021 5,978 5 View

Can linear DNA be used as template for site-directed mutagenesis?

Is it possible to induce site-directed substitution mutation by quick-change method on linear dsDNA? or it has to be cloned in some vector? If yes, should it be treated with the Dpn1 enzyme...

03 March 2021 401 4 View

How to normalise data on OPM package from R Studio ?

Good afternoon, I recently used OmniLog from BIOLOG for my experimentations : I tested the metabolism of different strains on 2 types of plates. I have 16 strains of 3 different groups...

02 March 2021 3,584 1 View

How to repeat an operation on an atom selection for multiple times in PyMol?

Hi, I am trying to construct a multi-layer fibril structure from a single layer in PyMol by translating the layer along the fibril axis. For now, I am able to use the Translate command in PyMol...

02 March 2021 4,569 4 View