Upto what concentration of Nanomaterials the toxicity study should be carried out?

22 May 2019 1 4K Report

I have synthesized the magnetic nanoparticles for radiotherapy application. I have to check their toxicity before studying radiosensitization. But in literature there is no agreement with the concentration chosen for the toxicity study. However, I am planning to take the concentration range of 0 to 200 micro gram per ml based on majority of the study. Is this concentration range appropriate?

Gary Joseph Ordog

Your problem is, in theory there is no threshold. Fortunately, for you governments usually set practical thresholds. Personally, I would not go above pico levels, but that's just my impression, nothing legal.p

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