Hi all,

I have a question about my analyses for a revise and resubmit I am working on.

I have a predictor and two moderators I am testing on my outcome (which has several dimensions - so multiple regressions).

For the analyses: for each outcome, I ran several moderated regression analyses.

To test the first interaction (predictor x moderator 1), I did the following:

In block 1:

predictor

moderator 1

moderator 2

And then in block 2:

added predictor and moderator 1 interaction (predictor X mod1)

To test the other interaction (predictor x moderator 2), I ran a SEPARATE linear regression.

In block 1:

predictor

moderator 1

moderator 2

And then in block 2:

added predictor and moderator 2 interaction (predictor X mod2)

One of my reviewers says that both interactions should be included in the SAME model.

When I tested this, interactions that were significant are no longer significant (because including BOTH interactions takes away explained variance).

My question is -- when testing multiple moderators, do they have to be included in the same model? By testing all moderator effects together, I lose the explained variance.

But I am not aware of what is best practice. To me, it makes sense to test in two separate models (one for each moderators).

Only one reviewer wanted this, and the other didn't mention it.

Any insight or help is much appreciated. Thanks!

Erin

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