Hi everyone,
I have a task for my college study, about the formulation of sublingual tablet. can anyone tell me about what is actually the sublingual tablet is, like the characteristics, what the requirement for the substance that can be formulated as a sublingual tablet, what the evaluation test that should be we do after the production?
and maybe someone knows the literature that i can read it, especially about sublingual tablet formulation.
Thanks.
these are formulated for the drugs which need to be rapidly up taken and delivered directly to the blood stream, as sublingual part is having high degree of vascularization, so the drugs can be rapidly delivered. Also this route passes the first pass metabolism of the drugs delivered. e.g. nitroglycerine sublingual tablets
Drugs having lower dose, problem with oral formulation, problem of first pass metabolism, irritation in GI tract can be converted for sublingual tablet formulation.
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