can anyone give me examples of its toxicity and can it be rank from its severity?
Dear in clinical and pre clinical is clear due to pathogenicity and causes
the maternal toxicity the cause due to dam toxicities that may be cause both fetotoxicity and teratogenicity; the fetotoxicity, the fetus is not die may be cause teratogenicity clinically or laboratory .... in coniclued that terms flow sequence each cause and pathogenicity
Suggested citations and references therein: Black, D.A. and T.A. Mark's (1986) Inconsistent Use of Terminology in Animal Developmental Toxicology Studies: A Discussion. Teratology 33:333-338. Black, D.L. and T.A. Marks (1992) Role of Maternal Toxicity in Assessing Developmental Toxicity in Animals: A Discussion. Regul. Toxicol. Pharmacol. 16:189-201. Marks, T.A. (1991) A Retrospective Appraisal of the Ability of Animal Tests to Predict Reproductive and Developmental Toxicity in Humans. J. Am. Coll. Toxicol. 10: 569-584.
In order to explain without too much confusion:
fetotoxicity is any modality influencing -poisoning an otherwise healthy embryo and harm (even kill) it.
Teratogen is any chemical , biological or physical factor capable of causing congenital anomalies or birth defects. not necessarily killing them.
maternal toxicity is usually referred to chemical agents that influence the health of the mother. It may or may not harm the embryo / fetus directly but usually effects the fetus somehow indirectly . The definitions may look similar and may be slightly different in various sources.
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