Hello everyone i read number of articles but everyonechoosed diffirent dossage and route of administration but which is the best dossage creating testicular toxicity in rats and route of adminstration..
I have no information if there is any difference in the testicular toxicity observed due to lead acetate administration in rats. If you have, please share.
However, a simple theory is that you should choose the most convenient route of administration, if it doesn't effect the results. In this case, I would recommend that oral gavage will be the best route for repeat dose administration and would produce least stress to animals.