You might want to get in touch with Dr. Refinetti, friend and colleague of mine. He has developed programs. He should also know other commercially available programs:

http://uscsalkehatchie.sc.edu/home/2011/06/roberto-refinetti-2/

Thank you a lot, I will contact Dr. Refinetti

Dear Aleksander, Cosine fitting is well tried and gives the necessary output variables. See our paper: Coffee in the cornflakes: time-of-day as a modulator of executive response control. Neuropsychologia. 2002;40(1):1-6. At the time we wrote our own software and used SPSS, however now CircWave, Chronolab and CoSOPT are available. Hope this helps. Best wishes

Thank you very much, I'll try a few of them.

The R package offers a few useful functions for circadian rhythm analysis.  These include spectral analysis (http://www.stat.pitt.edu/stoffer/tsa3/index.html)., Cosinor function (https://personality-project.org/r/html/cosinor.html). See also the JTK_Cycle algorithm ( Hughes ME, Hogenesch JB, Kornacker K. J Biol Rhythms. 2010 Oct;25(5):372-80), and Wavelet analysis.  http://www.ncbi.nlm.nih.gov/pubmed/18931366

Dear Aleksander

For the beginners"The circadian physiology by Refenetti  book is better, there you can find the software and also gives good education on how to  collect the data and which is the suitable analysis for the data. It also depends upon the organisms that you are using for the study.

You may try http://564394709114639785.weebly.com/

Hi!

I recommend you the plug in for image J "actogram J". Is only fr baiuc analysis

The following articles are a good source to guide the analysis of data from chronobiologic projects:

- Refinetti R, Cornélissen G, Halberg F. Procedures for numerical analysis of circadian rhythms. Biological Rhythm Research 2007; 38 (4): 275-325.

- Cornélissen G. Cosinor-based rhythmometry. Theoretical Biology and Medical Modelling 2014; 11: 16. doi:10.1186/1742-4682-11-16. 24 pp.

- Lee Gierke C, Cornélissen G. Chronomics analysis toolkit (CATkit). Biological Rhythm Research 2016; 47: 163-181.

I would recommend the software El Temps, from Antony Diez-Noguera (University of Barcelona). So far, it is the most complete suite for Chronobiology analysis.

CATkit in R offers a suite of cosinor programs for the characterization of circadian rhythms and rhythms and also of rhythms with other periods.

Hi all - I was wondering if anybody have access to a user manual for the software El temps? I can't seem to find one and it is not very user friendly to begin with.

Thanks!

Try out RhythmicAlly

https://doi.org/10.1177%2F0748730419862474

The following publication discusses relative merits of different software packages available for rhythm assessment:

Cornelissen G. Applications of cosinor rhythmometry in pharmacology. Journal of Pharmacokinetics and Pharmacodynamics 2021; 48: 339–359. https://doi.org/10.1007/s10928-021-09748-x(0123456789().,-volV)(0123456789().,-volV)