I have the case example of running a logistic regression with a binomial response variable and a categorical predictor, with data organized in a contingency table. Are there any formal or practical pros/cons for using sampled parameters (e.g. sampled total) vs. unbiased estimates (e.g. a Total calculated from the same dataset with a Horwitz-Thompson estimator)? Would the choice affect the results of the logistic regression?

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