Hi, I hope to receive your help. I am a student, so I do not have a lot of experience in research. If you wanted to understand how RNAP, ribosome, and transcription factors work altogether and communicate with each other in prokaryotic, how would you set your research project? I thought to purify each component of the expressome, mix them to create the supramolecular complex and use CryoEM. What do you think? Any alternative ideas?