I am working with a Peptide that targets renal carcinoma. I have checked the binding with 769-P cells in vitro. Now i want to develop an in vivo tumor model using 769-P cells. But most the researchers use 768-O cells for renal carcinoma in vivo model.
Is there any specific reason to use 768-O cells instead of 769-P cells ? Can i have some in vivo model of 769-P renal carcinoma?
We do commercial 786-O xenografts (http://altogenlabs.com/xenograft-models/kidney-cancer-xenograft/786o-xenograft-model/) mainly because they are well characterized and are easy to deal with in cases where there are errors in growth/function. 769-P isn't all that different, and we could run a 769-P xenograft if your research requires it.
Dear Enamul,
perhaps this paper gives you an idea?
Article Overexpression of SEPP1 inhibits the proliferation and induc...
We do commercial 786-O xenografts (http://altogenlabs.com/xenograft-models/kidney-cancer-xenograft/786o-xenograft-model/) mainly because they are well characterized and are easy to deal with in cases where there are errors in growth/function. 769-P isn't all that different, and we could run a 769-P xenograft if your research requires it.
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