Estimating rate of insulin resistance in patients with preeclampsia using HOMA-IR index and comparison with nonpreeclampsia pregnant women.Abhari FR et al. Biomed Res Int. (2014)
Relationship between insulin resistance and tissue blood flow in preeclampsia.Anim-Nyame N et al. J Hypertens. (2015)
In preeclampsia, there is exacerbation of physiological changes associated with pregnancy such as insulin resistance, altered immune responses and inflammatory pathway activation. These exaggerated responses seen in preeclampsia are reminiscent of metabolic syndrome, and also are evident in gestational diabetes mellitus. The link between these phenomena is not clear but novel findings providing some insight have been reported recently. Inositol phosphoglycan P-type (P-IPG) in preeclampsia has been extensively investigated and increased production has been demonstrated. This molecule acts as a second messenger of insulin, enhances the metabolic effects of insulin and is associated with insulin resistance. This review article summarizes current evidence of the role of inositol phosphoglycans in the metabolic syndrome that occurs in preeclampsia, discussed in the light of modifications found in gestational diabetes mellitus and diabetes type 2 in pregnancy in humans and animal models. An increase in urinary release of P-IPG during pregnancy may herald the onset of preeclampsia. Further knowledge about the nature of the metabolic syndrome during preeclampsia and the degree of association between its components will help to inform future research efforts and to identify biochemical markers that could help in clinical practice, for example early markers that will have utility in managing disease progression.
Preclampsia apart from other associations is due to raised blood pressure. Raised blood pressures are parts of the definitions for metabolic syndrome (Insulin resistance syndrome) so i guess its simple Yes.
Already some evidence have been shared, and here is something which adds to it in terms of mechanism and related fetal and maternal side effects:
1- Armanini D et al. Maternal and Fetal Outcomes in Preeclampsia: Interrelations Between Insulin Resistance, Aldosterone, Metabolic Syndrome, and Polycystic Ovary Syndrome. J Clin Hypertens (Greenwich). 2015 Oct;17(10):783-5. doi: 10.1111/jch.12613.
2- Solomon CG et al. Brief review: hypertension in pregnancy : a manifestation of the insulin resistance syndrome? Hypertension. 2001 Feb;37(2):232-9.
3- Seely EW et al. Insulin resistance and its potential role in pregnancy-induced hypertension. J Clin Endocrinol Metab. 2003 Jun;88(6):2393-8.
4- Anim-Nyame N et al. Relationship between insulin resistance and tissue blood flow in preeclampsia. J Hypertens. 2015 May;33(5):1057-63. doi: 10.1097/HJH.0000000000000494.
So whatever i searched on pubmed was all supportive of the link between the two entities.