I would like to compare the absorbed doses and cancer risk between MIBG I-131 and MIBG I-123 but the problem is that dose data for MIBG I-131 are compiled from ICRP Publication 53 which are based on the ICRP Publication 60 methodology. For MIBG I-123 I managed to find the recalculated dose data based on the ICRP Publication 103 methodology. I wonder where I can find the recalculated dose data for MIBG I-131? Or can I use the absorbed doses table for I-131 (table C109) from ICRP Publication 128 to estimate the MIBG I-131 absorbed doses? Also it seems that the ICRP has changed the biokinetic model for iodide should I use the absorbed doses table for I-123 (table C106) to estimate the MIBG I-123 absorbed doses?Why ICRP did not provide the intravenous administration absorbed doses for 131I-iodide?
NaI injection
http://www.ansto.gov.au/__data/assets/pdf_file/0008/50201/PI_I131_Injection2011.pdf
may be helpful
ICRP Publication 128 is a compendium of current information on dose to patients from radiopharmaceuticals based on the ICRP Publication 60 methodology. The data are mainly compiled from ICRP Publications 53, 80, and 106, although there is also the new information for 82Rb-chloride, iodide (123I, 124I, 125I, and 131I) and 123I labelled 2β-carbomethoxy 3β-(4-iodophenyl)-N-(3-fluoropropyl) nortropane (FP-CIT). The coefficients tabulated in ICRP Publication 128 will be superseded when the new calculations using pediatric and adult reference phantoms and the ICRP Publication 103 methodology become available.
Check the SNM dose calculator:
http://www.snmmi.org/ClinicalPractice/doseTool.aspx
It derives the dose from 131I-MIBG from ICRP 106.
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