Hi everyone,

I’m planning to extract total RNA from Staphylococcus samples for transcriptomic profiling, but this is my first time doing RNA extraction. I’ve heard great things about the QIAGEN RNeasy kits, but the cost is a bit steep, especially when factoring in the RNAprotect Reagent and DNase Set.

I came across the NEB Monarch Total RNA Miniprep Kit, which includes gDNA Removal Columns and DNase I at a more affordable price point. Does anyone have experience with the NEB kit? How does it compare to the RNeasy in terms of performance and ease of use?

Thanks in advance!