I have searched in ExPASy about the sequence of Minnelide or Triptolide. Can any one suggest where I can find the protein sequence of those two. And please let me know, if genome sequence of Tripterygium wilfordii is available.
Regards
NZ
It can't be specified much further. They are simply small-molecule compounds i.e. like aspirin, sunitinib, staurosporine, and most other drugs that you are aware of. They are not made up of a chain of amino acids so they are not proteins and you will not be able to find them in any protein database. You likely will find them on pubchem.
http://en.wikipedia.org/wiki/Triptolide
https://pubchem.ncbi.nlm.nih.gov
Search in PubChem, DrugBank, ZINC databases. You can surely find the desired molecules there.
Is it possible that you are referring to organisms that originate these molecules to oncological applications ?
You can reconstruct the protein/gene sequence of their key genes in the link above, at UniProt web service
http://www.uniprot.org/uniprot/?query=organism:tripterygium&fil=organism%3A%22Tripterygium+wilfordii+%5B458696%5D%22&sort=score
Dr. Castaldi, yes you are right, I want to study oncological applications
& Thanks everyone. I will try those out for sure.
Thanks for the feedback Nayem, it was a pleasure.
Have a good research!
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