To determine probiotic properties of bacterial isolates some tests such as aggregation test e.g., auto-aggregation and co-aggregation tests are applied.
Hovewer, based on my best knowledge, I did not find any limitation for these two values. For example, In the same study, aggregation values may change between %20 to %60, but what is the limitation for this? Should I considered %20 aggregated bacterie as a probiotic strain?
Thanks.
Auto-aggregation and co-aggregation are strain specific attributes. Usually they are higher in probiotics than pathogens. I proposed you these articles:
Thank you for your answers. I mean that there should be a critical value to accept or not as a probiotic for bacterial evaluation. Not only for aggregation but also for other criterias for assessment of probiotic properties.
Some researchers have indicated reliance on clinical trials to make more final recommendations.So, Sometimes a probiotic "cocktail" is used that consists of different strains
I suggests this attachment
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053917/
Dear Gokirmakli
Presence some criteria such as stability in assimilated gastrointestinal conditions (Acidic pH (2-3) of stomach, Bile tolerance (0.3%)) , animicrobial effects against pathogens and aggregation rate (strain based 20-70%) of studied strains are used to introduce a microorganism as probiotic.
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