Lectin transcripts have been implicated in the innate immune mechanisms of invertebrates. I have studied its function through gene-silencing mechanisms. I need to devise strategies to over-express the lectin transcripts in vivo to act as a therapeutic strategy. How do I do that?
Dear Dr. Bharat,
Find a couple of papers which could give you some idea,
H Rechreche, GV Mallo, G Montalto, Cloning and expression of the mRNA of human galectin‐4, an S‐type lectin down‐regulated in colorectal cancer,Eur. J. Biochem. 248, 225-230 (1997)
NSC Wong, MGS Yap, DIC Wang,Enhancing recombinant glycoprotein sialylation through CMP‐sialic acid transporter over expression in Chinese hamster ovary cells, Biotechnology and Bioengineering, Vol. 93, No. 5, April 5, 2006,- Wiley Online Library
Good luck!
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