i am getting three spot after my reaction of aldehyde, ethanol and 2-aminothiazole derivatives. so i feel is because my amine is not soluble in ethanol. so can i use ethanol and DMF, Is this good
Third spot may be because of auto oxidation product of aldehyde. Take tlc of pure aldehyde which you used for the reaction.
I synthesized schiff base by reaction of thiazole derivative of sulphonamide with aldehyde. A yellow solid was obtained using ACN as solvent. The mass spectra confirmed the m/z but there is no peak for CH=N (around 8.5 and above).please can someone help me to justify that it my compound that I synthesized.
You'll have to provide structures and spectra - there's no way to answer your question without that information.
Try Solvent free synthesis by microwave irradiation
The microwave assisted syntheses of Schiff bases from different aldehyde and amines is carried out efficiently and high yield of product in short time has been obtained
Hi, i advise you to dissolve your amine in few quantities of DMF and complete the rest by methanol. i try it and i get best yield. Or, you can use solvent-free technique.
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