it is quite simple, although if it is your first time doing it may seem a bit complicated.
In DesigModeler or in Workbench Meshing, you can create a set of faces name selected which will compose you interfaces. One name selected for each side of the interface. Then in fluent in Boundary Conditions you pick your boundaries and change them for interface (under type). Go to Mesh Interface and create each pair of interface you have.
The tip speed you can calculate based on your rotation velocity and impeller diameter and enter with the rotation in Cell Zone Condition for your rotation region. MRF is the first option called frame motion. Send me an email if you need further help, I'm glad to help. ([email protected])