Nature of solvent, solvent ratio, temperature and time of maceration process. From the previous literature it was seen that some scholars linked it with other parameters like enzyme and pH balance, so optimum enzyme and pH conditions/factors can also affect maceration extraction for the maximum release of bio-actives. spinning speed or homogenization time can be taken as other prime factors.
above all factors, saturation and pressure is also influence the rate of separation, gravity fed no matter, but in some cases pressure is applied to enhance the outcome.