How to design ion NIPT in Ion Proton NGS?

1. Does thermofisher provide ready to use primer mix for NIPT? or the user has to define the list of primers? 2. Did ion community already design NIPT? 3. What is the method of analysis? 4. what...

09 October 2017 840 1 View

What was the first cancer for which genetic marker was identified?

06 July 2017 6,993 4 View

What will happen, if any alkaline earth metal is used in a PCR reaction mix instead of MgCl2?

Magnesium is an alkaline earth metal and its electron configuration is 2,8,2. All other alkaline earth metal such as calcium(2,8,8,2), strontium(2,8,18,2), barium(2,8,18,18,2) has a similar...

07 August 2016 2,129 5 View

What are the low impact factor cancer journal?

07 August 2016 9,400 0 View

What are the excitation spectra of N-Methyl mesoporphyrin in a flurometer?

In my current study, I am using NMM as fluorescence material. Most of the previous study mentioned the excitation spectra of NMM is 399nm and the emission spectra is 610nm. Is it possible that I...

06 July 2015 5,903 4 View

How to accurately identify cancer tissue origin with MicroRNAs?

In this article fig. 1. The Author has made a decision tree with 24 nodes. Each node is specified for a specific cancer tissue of origin and the couple of MicroRNA which can identify these cancer...

05 June 2014 5,962 4 View

Is it necessary to have the same type of samples in a case control study?

For an example: I want to study rsxxxxxxx SNP in Indian population. I have FFPE samples obtained from NSCLC patients. Which kind of control samples should I procure? Is it necessarily to be a FFPE...

04 May 2014 5,089 16 View

How do I calculate desired sample size for a case control study?

For an example, I want to study rs2910164 in Indian NSCLC patients. How do I calculate the desired sample size to get a significant power in the study?

04 May 2014 4,815 8 View

How can I differentiate or identify metastatic cancer cell from a non metastatic cancer cell?

Is there any gold standard method of identifying a metastatic cancer cell from a non metastatic cancer cell? Is there any molecular assay available to differentiate these two type of cancerous cell?

04 May 2014 6,071 6 View

How can I decrease the CT value of U6snRNA?

I am facing some problems while performing rt-PCR of mir205, 196b, 375, 21 and u6snrna. Every time the CT value of u6snrna is more than 33 and sometimes it is closer to 37. I have extracted whole...

01 February 2014 8,583 12 View

error in running a model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

error in modelling model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MGL tools

20 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

i have some problem with chtMultiRegionSimpleFoam

--> FOAM FATAL ERROR: Maximum number of iterations exceeded From function Foam::scalar Foam::species::thermo::T(Foam::scalar, Foam::scalar, Foam::scalar, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar) const) const [with Thermo = Foam::hConstThermo >; Type = Foam::sensibleEnthalpy; Foam::scalar = double; Foam::species::thermo = Foam::species::thermo >, Foam::sensibleEnthalpy>] in file /home/ubuntu/OpenFOAM/OpenFOAM-4.1/src/thermophysicalModels/specie/lnInclude/thermoI.H at line 66. FOAM aborting #0 Foam::error::printStack(Foam::Ostream&) at ??:? #1 Foam::error::abort() at ??:? #2 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::calculate() at ??:? #3 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::correct() at ??:? #4 ? at ??:? #5 __libc_start_main in "/lib/x86_64-linux-gnu/libc.so.6" #6 ? at ??:?

24 March 2021 0 0 View