How can I treat patient with post treated HCV mixed cryoglobulinemia relapse after sof/dakla after SVR, 6 months... Presented with peripheral neuropathy and can't stand or walk with PCR HCV RNA negative with positive cryoglob. With high tire?
Dear doctor Hassan.
As regarded to patients with peripheral neuritis due cryoglobulinemia after eradication of HCV by DAAS we can try immune suppressive as azathioprine or cyclophosphamide and corticosteroids or rituximab
cryoglobulinemia (MC), recognized as the most common HCV-induced extrahepatic disease, is an immune-complex-mediated vasculitis involving small vessels characterized by an underlying B cell proliferation
HCV is a positive strand RNA virus with a 9.6 kb genome that replicates predominantly in the liver. HCV frequently causes extrahepatic manifestations, the most common and severe of which is mixed cryoglobulinemia (MC), a systemic vasculitis affecting small- and medium- sized arteries and vein
cryoglobulinemia is a rare disorder characterized by the presence of cryoglobulins in the blood. Cryoglobulins are abnormal proteins that thicken and clump together at cold temperatures, usually below 98.6 degrees Fahrenheit (the average human body temperature)
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