We performed two independent Lumineex assays.

In the first we measured 34 analytes and for the second 15 analytes (included in the first 34).

Thus, we have a first dataset (lm1) with data of 15patients for 34 analytes and a second dataset (lm2) which contains data for new patients (7) and patients already analysed in lm1 (7patients) for 15 analytes (the same of the first 34 analytes).

We wanted to merge these two datasets, but the common data between lm1 and lm2 are not equal. Although, they maintain the tendencies, the absolute values are much lower in the lm2 than lm1.

What would you use to merge these two datasets? Z-score? Mean of common patients between lm1 and lm2? Normalize the values of lm2? How?

Thanks for your time!