Measles in the vaccinated population is very much reported in the published literature. However, basically clinical protection depends on the circulating antibodies (protective titres) and memory T/B cells. After one dose of vaccination, chances of non-responders (primary vaccine failures) are high compare to two dose recipients. Concept of waning immunity has been described in the vaccinated population , therefore in some situation introduction of third dose is advised.
However, two doses before school entry may produce very high level of circulating antibodies and ultimately protect from the clinical measles in future.
Antigenically, measles is a monotypic virus and all circulating wild types can be taken care by the vaccine strains (excellent live attenuated vaccines are available in the market).
Yes, because no vaccine is 100% effective. World Health Organization (WHO) estimates that about 95% of individuals who receive the measles vaccine are protected from infection.
It's possible, but very unlikely. The combination measles-mumps-rubella (MMR) vaccine is a two-dose vaccine series that effectively protects against all three viruses.
In fact, more than 93 percent of people who get the first dose of MMR develop immunity to measles. After the second dose, about 97 percent of people are protected.
The first dose of the MMR vaccine is recommended for children ages 12 months to 15 months. The second dose is recommended before your child begins kindergarten or first grade, around ages 4 to 6. If needed, however, the second dose can be given as soon as four weeks after the first dose.
Your child may need the second dose at a younger age if you plan to travel abroad. Infants ages 6 months to 11 months should receive one dose of measles vaccine before traveling.
The combined measles-mumps-rubella-varicella (MMRV) vaccine is another option for children that also protects against chickenpox (varicella). It's a single shot that may be used in place of the MMR and chickenpox vaccines. Talk to your doctor about both options.
If you're a teen or adult who isn't sure whether you've been properly vaccinated against measles, talk to your doctor. A blood test can confirm if you already have immunity from a previous vaccine.
If the test shows you don't have immunity, and you're a teen or young adult living in dormitory, your doctors will likely recommend that you get two doses of vaccine at least four weeks apart. Adults who don't have immunity are advised to get at least one dose of MMR vaccine. Your doctor can recommend what's best for your individual situation.
According to my knowledge, when anyone got vaccinated against measles, just one shot is necessary to be protected for his lifespan, the second shot that is recomended in diferents countries is not a booster but it is recommended to cover the missed persons by the first shot or primary vaccine failure, this because the vaccination coverage rate must reach 90% - 95% to avoid measeles epedemics as the prevalence of measles is very high.
N.B: the 1st shot mut be betwen 9th and 11th month when the enfant immunity is matur and the maternal antibodies rate is low, the second shot is generaly carriedout in the 18th month.
The combination measles-mumps-rubella (MMR) vaccine in a two-dose vaccine series effectively protects against all three viruses , almost 98%-100% of the subjects vaccinated
Yes you can, because the first vaccination of measles protects only 80% of population vaccinated. And you'll be or not on in this population. It is because of that we have the second vaccination which protects 95% of population.