Lately I find many cases of low growth in girls (3-4 years old) who also have high blood cholesterol. Could there be a relationship? I can't find studies that associate these two factors and the similarity of the chemical structure with vitamin D is what comes to mind.
Please go through the following links.
http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.594.4645&rep=rep1&type=pdf
https://academic.oup.com/ije/article/32/6/1110/775186
Dear colleague,
You pose an interesting question.
High blood cholesterol is a risk factor even in kids, but I have never heard of growth retardation due to a surplus of cholesterol being a building 'brick' for cells.
Concerning vit D and high cholesterol: vit D in our body mainly results from UV radiation of 7-dehydrocholesterol in the skin. Vit D metabolism is highly regulated and unless vit D is very low, there is no effect of vit D on growth. So I believe no relationship between high cholesterol and low growth is to be expected based on involvement of vit D.
I think you should focus on the cause of the high cholesterol. Is there also massive adipositas (that is associated with low vit D).
Thank you.
They are normal weight girls, most of them with a correct diet. They have not history of hypercholesterolemia in the family...
I read about GH and cholesterol in adults but not in children
Please go through the following links.
http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.594.4645&rep=rep1&type=pdf
https://academic.oup.com/ije/article/32/6/1110/775186
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