Looking for studies about angiotensin II receptor type I binding by non-radioactive methods

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Can anyone suggest me best esterification reaction?

For my esterification reaction, I choose Quinoline carboxylic acid which is highly polar and water soluble. I choose tert-butanol as alcohol, with DMF as Solvent and DCC and DMAP (Steglich...

01 February 2017 5,370 15 View

Can anyone help me in the synthesis of 2 amino 1,3,4- thiadiazole from thiosemicarbazone?

Cyclization of thiosemicarbazone to 2 amino 1,3,4- thiadiazole methods from aromatic aldehydes.

03 April 2014 9,304 6 View

Can someone advise on finding possible metabolites for Phase I and Phase II for any drug online?

Is there any link available?

06 July 2013 734 2 View

Can anyone help me in intrepreting the results of real time PCR?

How to intrepret results for Normal PCR and Real Time PCR? How to differentiate them? Kindly give basic differences between the two PCR's? Attach any kind of manual or publication details...

02 March 2013 7,753 5 View

Which software best suits molecular docking and computation chemistry?

Looking to buy the best computational and molecular docking studies for my QSAR studies for my molecule.

01 February 2013 3,216 11 View

Can anyone help me out by giving details about where I can procure spontaneous hypertension rats for my research purpose in India?

For hypertensive model.

31 December 2012 7,975 3 View

Can Any one help me out in selective methylation of Pholoroglucinol in the preparation of isoflavonone

I have to add methyl group in the para position of Pholoroglucinol after forming isoflavonone

11 December 2012 4,876 0 View

Reagent useful for cyclization of Chalcones to isoflavones with good percentage of Yield

I have tried with BF3 Etherate (Freshly Distilled) and MOMCl protection method but of no use yield was so less

11 December 2012 8,370 1 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

16 June 2021 0 0 View

fatal error

16 June 2021 0 0 View

fatal error

16 June 2021 0 0 View

flexibility of polymers chain

effect of double bond on the flexibility of polymers

07 April 2021 0 0 View

Formulation of polymer color flakes

I am writing to request some information for making polymer color flakes. I would appreciate the help.

17 March 2021 0 0 View

Buffer to disrupt platelet alpha granules for PF4 quantification?

Hello! I want to quantify by ELISA the secreted (from platelets poor plasma) and the non-secreted (from platelet lysate) PF4 before and after TRAP stimulation. I will use the ELISA from R&D...

03 March 2021 1,499 2 View

Sample dilution for quantitative analysis using ELISA?

If the detection range is in ng/ml but the reference range is in ug/ml for a molecule or protein in serum or plasma .how to dilute and what is the initial volume to be taken for quantitative analysis

02 March 2021 7,670 3 View

Pedro D'Orléans-Juste

Hello,

May I suggest that you contact Dr Emanuel Escher ([email protected])? He is a medicinal chemist who has contributed significantly in the development of binding assays of both AT receptors at the cellular level.

Regards,

Pedro

Anvesh Jallapally

Thank you prof. pedro.

Romer Gonzalez-Villalobos

Check on this paper: PMID: 15467006. I went trough the process of studying Ang II binding by non-radioactive methods.