Can anyone help me find a study of the lead toxicity and LD50 for oral route for mice. I found some references for lead toxicity in rats, for intraperitoneal route, but none for oral route in mice.
You can convert the dose from rats to humans. Then converted back into mice
According to Morkonda Rajaram Srinivasan
Human dose (mg/kg) to mouse dose (mg/kg) - multiply by 12.3
Human dose (mg/kg) to rat dose (mg/kg) - multiply by 7.4
Human dose (mg/kg) to guinea pig dose (mg/kg) - multiply by 4.6
Human dose (mg/kg) to rabbit dose (mg/kg) - multiply by 3.1
Human dose (mg/kg) to dog dose (mg/kg) - multiply by 1.8
In your case:
To convert the dose from rats to mice multiply by 12.3/7.4 = 1.66
Look at this pages
https://www.researchgate.net/post/How_to_convert_human_dose_to_animal_dose
https://www.researchgate.net/post/How_can_I_convert_mice_dose_to_rat_dose
https://www.researchgate.net/post/How_to_convert_rat_dose_into_mouse_dose
Oral LD50 for Lead Stearate in mice = 10428 mg/kg
-http://www.t3db.ca/system/msds/attachments/000/001/708/original/T3D1324.pdf?1413587731
For lead acetate, Intraperitoneal (mouse) LD50: 174 mg/kg
http://www.anpel.com.cn/UpFile%5CStock%5C201405%5CMSDS-4.120009EN.pdf