The optic nerve unidirectional, it transmitting impulses from retina to brain the nerve fibbers reach to lateral geniculate body, from that it reaches to occipital lobe (cortex). that is vision centre.

The optic nerve is unidirectional. Of course, it is bidirectional electrophysiologically in vitro.

Maybe axonal transport or trans-synaptic transport will be bidirectional as other nerves. So, answers to your question will change whether you see the optic nerve itself or whole visual pathway. And also whether you call the transport of protein or something due to axonal flow " the information" or not.

Thanks for responding. I'm primarily interested in whether there are mechanisms that involve transmission of signals from the brain back to the retina, or if the visual pathway is purely unidirectional in function as is commonly assumed. It may be possible that ephrin ligands or other proteins could be used to invoke reverse signaling, but unless it actually had a natural role in the visual system, I wouldn't count that as bidirectional transmission of signals.

Thanks for sharing the article - I had heard a couple of references to potential feedback mechanisms to V1, but this is the most specific, and I've seen no references to anything earlier in the chain (particularly not across the optic nerve).

Another good example is the centrifugal vision system in birds, efferent communication from brain to retina. It provides an active feedback loop for ganglion cells and also affects eye growth.

Review:

http://www.ncbi.nlm.nih.gov/pubmed/21524338

Thanks - That's a great example, and one I had not found. Thanks for sharing!

As it turns out, subsequent research on a parallel track led me to the work of Gastinger et al (Retinopetal Axons in Mammals - Emphasis on Histamine and Serotonin), which specifically addresses transmission of signals from the brain back to the retina within mammals, including humans. They discuss the role this descending signal may have in day/night vision, light sensitivity, disk shedding, etc.

Link:

http://www.ncbi.nlm.nih.gov/pubmed/16877274