I am analyzing data from a field study. The main goal of this experiment is to understand what intervention can help increase students verbal reasoning.

There are 4 kinds of interventions (say Factor A,B,C,D)in total, the combination of which result in 6 experiment groups.

group1: no treatment; group2: A; group3: A +B; group4 A+B+C, group5: A+B+D, group6: A+B+C+D.

We randomly chose some schools and assigned them into 6 different groups. Students' verbal reasoning skills were tested before and after the intervention for each school.

I suggested simply compare group1 v.s. group2 to determine effect of A, group2 v.s group3 to determine effect of B; and use a 2*2 ANOVA on group 3~6 to determine main and interaction effect of C and D.

My co-author suggested that we should check out analysis for nested model. I am confused as whether or not this is a nested design and how should i change my analysis if so?

Any suggestion is highly appreciated!!

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