- Sometimes, research can be misdirected, as it has been in primary vascular headache. The Tertiary Headache Centres, a group of totally dedicated and committed scientists, enforce their understanding of this highly complex but integrated subject. The Authoritative SPLITTING of the International Headache Classification is based on pure phenomenology and has no pathophysiological basis or parallel in MEDICINE, and, therefore it is not possible that a distinct cranial physiological anomaly will be detected for every member of this Headache Classification.
- Headache Conferences discuss flimsy issues threadbare and have an existential interest thrust upon them and are, in a way, not academically free to untie the Gordian knot of migraine and its sisters.
- Are there not scientists, physicians, neurologists, ophthalmologists in this world in this generation who would like to raise their voices and force the International Headache Societies to rationalize headache science by a steady and sensible re-grouping.
- The nosologic setback by splitting makes the evolution of a central integrated over-arching generalizable and predictive model for migraine impossible. "New" and "ïn-fashion" or "vogue" is nosophysiology but not pathophysiology.
- The interest of the Tertiary Headache Centres is to investigate psychophysical differences between migraine and tension-headache (TTH) with all possible technological measures available to them (have gadget, have statistics to lie with or misinterpret at will (Statistics are for prostitution-- a wag, now moving-with-the-times-be-forced-to-say bisexual prostitution), WILL publish OR PERISH) and to perpetuate this distinction to keep on publishing articles that carry little practical or therapeutic utility. Their arguments are always eloquent, seemingly futuristic, and always seek to justify their activities and existence but they never speak of the net results of ALL the huffing-and-puffing.
- With the advent of complex mathematization of medical sciences through statistics, medical research has become handicapped and progress is being stymied by big ideas. Now, as long ago, we have high priestesses and high priests who make profound mathematical statements in elaborate "doctored" charts to gasping audiences. When comprehension is cloistered rather than disseminated, only the eminences at the stage or podium understand what they are saying while ORIGINALITY GOES FOR A TOSS. Now, ONLY mathematics is ORIGINAL>PERIOD.
- Please read my note on noso-physiology in the BMJ about 10 years ago that you will find in my enlisted publications at ResearchGate.
- Please remember that PEG (the obsolete Pneumoencehalography) was the recommended management for cough-induced headache and was mentioned in headache/neurological periodicals till not very long ago. IT IS THE DEVIOUS CONVEYANCE OF RELIGION-LIKE BELIEF-IN-BELIEF CONVICTION BY THE SINCERE AND SERIOUS-LOOKING THERAPIST THAT THOSE WHO DID UNDERGO PEG DID NOT FILE A CLASS ACTION FOR A BILLION/TRILLION DOLLAR EACH. AFTER ALL, IF YOU CANNOT BELIEVE YOUR OWN DOCTOR OR YOUR OWN NEW TRIALIST DOCTOR, WHO WOULD YOU BELIEVE IN, ANYWAY? Do read-up on my 2 articles on Benign-Cough induced headache -- EASILY ACCESSIBLE.
- To jog those who still feel they have no role, I attach my OPEN ACCESS article. See, how we recruit patients like cattle in randomised clinical trials, what we tell them about migraine that we DO know or we don't know, how we obtain their consent. SEE THE TRIAL AND ITS OUTCOME BECOMING MORE IMPORTANT THAN THE PATIENT.
- I advise all participants in RCT, (RANDOMIZED CONTROLLED TRIALS) especially in the advanced countries where the Law is the lady blinded by the sash -- who is still capable, in at least most cases not involving the mafia or the FBI or the Medical Device/Drug Industry-- of using her discretion swiftly) to insist for a legal WRITTEN AND SEALED AND ATTESTED clause that the published results will be despatched to each one of them within TWO days of publication of the OPEN ACCESS PAPER and discussed in person by A COMMITTEE IN VIDEO OF at least three independent non-trialist specialists -- who should constitute a NEUTRAL third party not having professed faith in the subject matter covered by the trialists.
- RCT uncontrolled, like the Wild West, is therapeutic MISADVENTURE. Pro-active bottom-line protectors have often if not always outwitted the law. We will talk about the FDA AND THE FRAUD OF META-ANALYSIS another day. And, of course, the HOLIEST-OF-HOLY cow of medical sciences, the MEDICAL JOURNALS themselves. Rennie Drummond's (Deputy Editor of JAMA fame) quote has not RUNG LOUD AND CLEAR: ":...the chief function of the Editor is to keep egg-off the faces of prominent contributors." My letter-to-the-editor of Circulation never saw the light OF PUBLICATION in the MIST Trial. I upgraded it to the review attached below. The TRIAL went to Court and ruined some lives in the whole process. Whose life is it, anyway? IT IS WHEN YOU HAVE ARRIVED AND YOUR MESSAGE CARRIES WEIGHT BEYOND LAW AND COMMON SENSE THAT YOU BECOME A TRUE THREAT TO SOCIETY.
- I ADVISE EVERY PATIENT WHO IS CONSIDERING ENLISTING IN AN RCT TO CAREFULLY READ THIS MESSAGE AND THE APPENDED ARTICLES AT LEAST A HUNDRED TIMES AND TO DISCUSS THE MATTER WITH THEIR LAWYER BEFOREHAND / BEFORE GIVING INFORMED CONSENT. LONG-AFTER I AM DEAD AND GONE, THIS MESSAGE WILL RESONATE FOR ALL FUTURE GENERATIONS OF DOCTORS AND PATIENTS. AS LONG AS I AM ALIVE, YOU CAN ALSO CONTACT ME BEFORE PARTICIPATION AS A GUINEA PIG IN RCT THROUGH THESE COLUMNS.
- In the meantime, can we please carry on with the oh-so-important differences between migraine and tension-type headache.
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