Dear Shankhadeep Chakraborty,

Absolutely harmless drugs do not exist. Medications other than the therapeutic effect, as a rule, have side effects, the possibility of manifestation that warns the physician prescriber and pharmacist in a pharmacy. Before using the product you must carefully read the instructions, which contains information about its side effects. Their severity depends on the dosage of the drug, the route of administration, duration of treatment, and body condition. Children and the elderly medication should be taken with extreme care, because they have side effects may appear particularly strong.

Manifestations of the side effects are often severe enough. Therefore, in all cases where you suspect that one or another ailment can be linked with taking drugs, it is recommended to consult a doctor.

Most side effects can occur even after a single admission medication (especially if the dose is exceeded). However, the probability of their manifestation and severity are largely dependent on the duration of the reception. Intensity of some side effects may be intensified or reduced in the course of treatment. And such side effects as addiction, drug dependence and accumulation (accumulation), may appear only after long systematic reception of medicines. Therefore, before starting a long course of treatment of one or another medication, be sure to consult with your doctor.

To reduce the possibility of side effects from the use of drugs should be aware of contraindications to it. About contraindications must tell the doctor, in addition, their list is always provided in the instructions to the drug.

The most common contraindications:

idiosyncrasy components of the drug;

hypersensitivity to the drug (substances that are part of it);

certain chronic diseases in decompensation or exacerbation stage (diabetes, asthma, heart disease, and others.);

pregnancy and lactation (for many medicines);

childhood

Regards, Shafagat

Dear Colleagues,

Good Day,

This is not my scientific field but I found really good article regarding the thread. Please,  try and see it:

"What is albuterol inhalation?

Albuterol is a bronchodilator that relaxes muscles in the airways and increases air flow to the lungs.

Albuterol inhalation is used to treat or prevent bronchospasm in people with reversible obstructive airway disease. It is also used to prevent exercise-induced bronchospasm.

Albuterol inhalation is for use in adults and children who are at least 4 years old.

Before taking this medicine

You should not use this medicine if you are allergic to albuterol. You should not use ProAir RespiClick if you are allergic to milk proteins.

To make sure albuterol inhalation is safe for you, tell your doctor if you have:

• heart disease, high blood pressure, congestive heart failure;
• a heart rhythm disorder;
• a seizure disorder such as epilepsy;
• diabetes;
• overactive thyroid; or
• low levels of potassium in your blood.

It is not known whether albuterol will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether albuterol inhalation passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Albuterol inhalation is not approved for use by anyone younger than 4 years old.

Albuterol inhalation side effects

Get emergency medical help if you have signs of an allergic reaction to albuterol: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• wheezing, choking, or other breathing problems after using this medicine;
• chest pain, fast heart rate, pounding heartbeats or fluttering in your chest;
• pain or burning when you urinate;
• high blood sugar - increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss; or
• low potassium - leg cramps, constipation, irregular heartbeats, fluttering in your chest, extreme thirst, increased urination, numbness or tingling, muscle weakness or limp feeling.

Common albuterol side effects may include:

• back pain, body aches;
• headache, dizziness;
• feeling nervous;
• nausea, diarrhea, upset stomach; or
• sore throat, sinus pain, stuffy runny nose."....

See the rest of the article.....

https://www.drugs.com/albuterol.html

Dear Shankhadeep, 

I learnt very soon, from my Medical course, that there is no medication without side-effects. (As they say, "even water, as it is essencial to life, can have a killing effect, if taken in excess, as in drowning...")

Dear Shankhadeep Chakraborty,

Absolutely harmless drugs do not exist. Medications other than the therapeutic effect, as a rule, have side effects, the possibility of manifestation that warns the physician prescriber and pharmacist in a pharmacy. Before using the product you must carefully read the instructions, which contains information about its side effects. Their severity depends on the dosage of the drug, the route of administration, duration of treatment, and body condition. Children and the elderly medication should be taken with extreme care, because they have side effects may appear particularly strong.

Manifestations of the side effects are often severe enough. Therefore, in all cases where you suspect that one or another ailment can be linked with taking drugs, it is recommended to consult a doctor.

Most side effects can occur even after a single admission medication (especially if the dose is exceeded). However, the probability of their manifestation and severity are largely dependent on the duration of the reception. Intensity of some side effects may be intensified or reduced in the course of treatment. And such side effects as addiction, drug dependence and accumulation (accumulation), may appear only after long systematic reception of medicines. Therefore, before starting a long course of treatment of one or another medication, be sure to consult with your doctor.

To reduce the possibility of side effects from the use of drugs should be aware of contraindications to it. About contraindications must tell the doctor, in addition, their list is always provided in the instructions to the drug.

The most common contraindications:

idiosyncrasy components of the drug;

hypersensitivity to the drug (substances that are part of it);

certain chronic diseases in decompensation or exacerbation stage (diabetes, asthma, heart disease, and others.);

pregnancy and lactation (for many medicines);

childhood

Regards, Shafagat

https://www.drugs.com/sfx/ventolin-side-effects.html

Changes in heart rate of approximately 20% may be produced by 0.18 mg of albuterol (the active ingredient contained in Ventolin) by MDI. Aggravation of angina may be due to tachycardia produced by albuterol. Atrial fibrillation was reported in one patient when a spacer device was utilized with an albuterol inhaler, thus increasing the available dose for systemic absorption. Supraventricular ectopic beats and ventricular tachycardia have also been reported. Higher doses of albuterol should be used with caution in patients with cardiac disease, arrhythmias, or hypertension. All of these effects are dose-related and lower doses may be tolerated.

The cardiovascular side effects have included palpitations, peripheral vasodilatation and reflex tachycardia with blood pressure increasing or decreasing. Albuterol in higher dosages has been reported to aggravate angina, myocardial ischemia, or cause atrial or ventricular arrhythmias. Pulmonary edema has been reported in pregnant patients receiving intravenous albuterol. Postmarketing reports have included hypotension.

yes some irritation may  occur 

Dear Shankhadeep Chakraborty,

When taken for many months or years, harmful side effects are likely and almost inevitable.

Inhaled corticosteroids have been the best treatment for asthma for more than 30 years. They are among the safest and most effective means to treat asthma. Although few side effects occur at standard doses (one to two puffs twice a day for most inhalers), some people may experience minor side effects such as hoarseness of the voice, and thrush (a yeast infection of the mouth and throat).

http://www.ucalgary.ca/asthma/files/asthma/leigh.pdf