Is there any recent study(ies) on developmental factors that could be responsible for or predispose an individual or a population to the development (early or late) of knee osteoarthritis?
There may be a multi-factorial interactive effect related to the predisposition as well as onset and progression of knee osteoarthritis. Each person's unique bone geometry and alignment and biomechanical stresses with walking and other activities as well as onset, type, intensity and duration of inflammation may also be related.
A study that has shed light on the stresses and strains on the cartilage within the knee joint is the following. I am sure there are many other quality articles out there. I hope this helps.
Effect of frontal plane tibiofemoral angle on the stress and strain at the knee cartilage during the stance phase of gait Nicholas H. Yang,,Hamid Nayeb-Hashemi1, Paul K. Canavan and Ashkan Vazir
Journal of Orthopaedic Research
Volume 28, Issue 12, pages 1539–1547, December 2010
Significant body weight as well as knee mal-alignment may also be a factor.
The Effects of Tibiofemoral Angle and Body Weight on the Stress Field in the Knee Joint Nicholas H. Yang, H. Nayeb-Hashemi and Paul K. Canavan
Paper No. IMECE2007-41344, pp. 103-111; ASME
Those recent articles may be helpful:
Bastick AN, Runhaar J, Belo JN, Bierma-Zeinstra SM. Prognostic factors for progression of clinical osteoarthritis of the knee: a systematic review of observational studies. Arthritis Res Ther. 2015 Jun 8;17:152.
Huétink K, Stoel BC, Watt I, Kloppenburg M, Bloem JL, Malm SH, Van't Klooster R, Nelissen RG.Identification of factors associated with the development of knee osteoarthritis in a young to middle-aged cohort of patients with knee complaints. Clin Rheumatol. 2015 Oct;34(10):1769-79.
Takacs J, Carpenter MG, Garland SJ, Hunt MA.Factors Associated With Dynamic Balance in People With Knee Osteoarthritis.Arch Phys Med Rehabil. 2015 Jul 14. pii: S0003-9993(15)00548-1.
Dear Gabriel
This article may be useful for you:
Osteoarthritis
MD Paul Creamer, Prof MD Marc C Hochberg
The Lancet Volume 350, No. 9076, p503–509, 16 August 1997
Hi Gabriel,
Following are some articles.
Ferraro B, Wilder FV, Leaverton PE. Site specific osteoarthritis and the index to ring finger length ratio. Osteoarthritis Cartilage 2010;18:3547.
Zhang W, Robertson J, Doherty S et al. Index to ring finger length ratio and the risk of osteoarthritis. Arthritis Rheum 2008;58:13744.
Haugen IK, Niu J, Aliabadi P, Felson DT, Englund M. The associations between finger length pattern, osteoarthritis, and knee injury: data from the Framingham community cohort. Arthritis Rheum 2011;63:22848.
Hussain SM, Wang Y, Wluka AE, et al. Association of low birth weight and preterm birth with the incidence of knee and hip arthroplasty for osteoarthritis. Arthritis Care Res. 2014
Hussain SM, Wang Y, Muller DC, et al. Association between index-to-ring finger length ratio and risk of severe knee and hip osteoarthritis requiring total joint replacement. Rheumatology (Oxford) 2014;53:1200–1207.
Individuals whom demonstrate a significant varus thrust during mid stance and whom have a genu varus presentation also tend to have a greater rate of progression of knee OA vs those with a more normal frontal plane alignment of the knee. Thus, both static and dynamic analysis are important.
Patellofemoral arthritis
1. Iriuchishima T, Ryu K, Murakami T, Yorifuji H (2015) The correlation between femoral sulcus morphology and osteoarthritic changes in the patello-femoral joint. Knee Surg Sport. Traumatol Arthrosc Springer Berlin Heidelberg
2. Jungmann PM, Tham S-C, Liebl H, Nevitt MC, McCulloch CE, Lynch J, Link TM (2013) Association of trochlear dysplasia with degenerative abnormalities in the knee: data from the Osteoarthritis Initiative. Skelet. Radiol 42:1383–92
3. Kalichman L, Zhang Y, Niu J, Goggins J, Gale D, Felson DT, Hunter D (2007) The association between patellar alignment and patellofemoral joint osteoarthritis features--an MRI study. Rheumatol. 46:1303–8
4. Stefanik JJ, Roemer FW, Zumwalt AC, Zhu Y, Gross KD, Lynch JA, Frey-Law LA, Lewis CE, Guermazi A, Powers CM, Felson DT (2012) Association between measures of trochlear morphology and structural features of patellofemoral joint osteoarthritis on MRI: the MOST study. J Orthop Res 30:1–8
In addition to the above presented information here are are few more publications"
(1) Aetiological Factors of Osteoarthritis: A Review Update
MJ Islam, MS Hossain, MR Amin… - Journal of Current and Advance Medical Research > Vol 2, No 1 (2015)
(2) Down-Regulation of Rac GTPase-Activating Protein OCRL1 Causes Aberrant Activation of Rac1 in Osteoarthritis Development. Zhu, S., Dai, J., Liu, H., Cong, X., Chen, Y., Wu, Y., Hu, H., et al. Arthritis & Rheumatology, 67: 2154–2163. doi: 10.1002/art.39174
(3) Elucidation of Dietary Risk Factors in Osteoarthritis Knee—A Case-Control Study. Divya Sanghi PhD, Abhishek Mishra, Amar Chandra Sharma, Saloni Raj, et al. Journal of the American College of Nutrition, Volume 34, Issue 1, 2015
(4) Diabetes is a risk factor for knee osteoarthritis progression. F. Eymard, C. Parsons, M.H. Edwards, F. Petit-Dop§, J.-Y. Reginster‖, et al.Osteoarthritis and Cartilage, Volume 23, Issue 6, 2015, Pages 851–859.
All the best.
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