Is there any reasonable method(s) for checking validity of phenotype using genetic data?

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Janneke Hogervorst

Dear Milad,

I think that validating your outcome by looking at genetic traits is not a good way. Most outcomes have multifactorial and multigenetic causes and a genetic trait is not often a necessary and sufficient cause for an outcome.

Babak Jamshidi

Machine learning possibly helps in these situations.