Can anyone refer to studies dealing with differentiation between human adipocytes and preadipocytes on the basis of cell diameter or cell volume?
Millipore evaluated the mean diameters of human adipose derived stem cells at 0, 7, and 14 days after the initiation of differentiation using the Scepter Cell Counter. Here is a link to the application note that describes the experiment and the results: http://www.millipore.com/publications.nsf/a73664f9f981af8c852569b9005b4eee/60a470cf77b4cda8852579e20063f2d5/$FILE/EM_AN3666EN00.pdf
That may not be exactly what you were looking for, but I hope it helps.
The simplest way to distinguish pre-adiposites/adiposites is to do a quick stain with Oil Red O (or similar lipid-specific dye). This will identify small lipid vesicles before they fuse and become obvious under light microscopy.
The typical mature adipocyte is relatively large (30–50 micron diameter) and can reach a size of greater than 120 µm under certain conditions. See also Morgado E et al., 1990, PMID 2152294, p.25 right column top paragraph: "Another exceptional cell type is the adipocyte (type N° 6). Its soma is comparatively larger (mean diameter between 30 and 50 µm)."
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