Fellow scientists, I'd like to know if a test solution contains certain leachates, meaning that an extraction method I am developing works. Much appreciated beforehand.
Very general question... what exactly are we talking about?
What substances are you working with?
What devices do you have?
Basically you need to apply the laser on the sample and measure the spectra, but there are a few parameters to be optimized in the process...
If you know what substances you're looking for, then first measure them pure, then measure your "mystery solution" and see if the same peaks come up. It may be quite complicated to QUANTIFY but just to know if something is there, this is the general approach.
You can also try and look up the pure substance fingerprints online, but it's always better to measure with your own device (deviations in wavenumber may need calibration).
In a nutshell, I want to extract plastic additives from micro plastics I created in the lab. I already have a protocol for extracting but I want to know if the additives are present in particle-free aliquotes of the solution. Should they be, I'd like to chategorize them and find them in an online library.
What substances are we talking about exactly, do you know?
There's a good chance it will be hard for you to find a good reference spectra but you could easily measure one yourself if you have pure substances in the lab (or you could maybe order them).
Then you will have a library of how they look in YOUR device, and you can also check your detection limit (by measuring at different concentration).