Dear all,
I am working with an exogenous protein that associates with mitotic chromosomes in HeLa cells. Now, I would like to find out whether this association is due to condensation of the chromatin itself, or is specifically mediated by proteins that are chromosomal during mitosis. Therefore, I am wondering whether there is a way to induce chromatin condensation independent of mitosis.
I would be very pleased to read your suggestions.
Best regards