Dear All,
I have RNA-Seq data from a patient cohort and for my analysis, i would like to exclude the genes and miRNAs which are specific for male and female. Hence, could you please suggest where and how i can get the list and most preferably im intersted in those genes/miRNAs whic are expressed in peripheral blood.
Thanks a lot.
Best regards,
Aravind
Usually I have found a bit of spurious transcription from genes on X and Y chromosomes even when they are not supposed to be.
A data driven way of obtaining such a list is doable via the GTEx data (www.gtexportal.org): Here you have data from many patients - especially from blod - where usually 1/3 is female.
To obtain the list simply calculate the average expression for all genes in male and female and look for those where there is a large log2FC.
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