Is the dose injected to the rats same as the dose injected to the mice or it should be different?

More Ayman Khalifa's questions See All

Good evening everyone can anyone send me SMC files of earthquakes of different intensities for a simulation on Plaxis 2D?

Good evening everyone can anyone send me SMC files of earthquakes of different intensities for a simulation on Plaxis 2D. Thanks

02 March 2024 4,362 1 View

Was the name of a researcher from Helwan University published on the website of most of my articles?

أخاطب السيدة المذكورة باسم Sarah Ayman بحذف اسمها من على الأبحاث الخاصة بى لأن هذا يعد انتحال علمى وسوف نبلغ جامعة حلوان بذلك

25 February 2024 7,614 1 View

We ask you to kindly change the information of the first name written incorrectly?

We ask you to kindly change the information of the first name written incorrectly as Sarah Ayman to the correct name as listed in the article, Ayman S Taha. Sincere thanks and appreciation.

25 February 2024 8,634 1 View

In the flotation process, what is the future effectiveness of using an activator reagents on copper oxide surface?

I know that many reagents are used as activators or enhancers (such as ammonium salts and so on) in copper oxide minerals processing to facilitate their flotability during the flotation process....

28 December 2023 2,694 0 View

In what cases is the phosphate group attached to carbon atom number 2 in nucleic acids?

I found this paragraph on page 223, Chapter 10, Concepts of Genetics. "The phosphate group may be bonded to the C@2′, C@3′, or C@5′ atom of the sugar"

27 September 2023 7,074 0 View

Transfection of neuroblastoma cell line (SHSY5Y) for RNA collection??

Usually neuroblastoma have low transfection efficacy (5-10%) when transfected with Lipofectamine 3000. So, this time I have tried electroporation with this condition, poring pulse: 175V, 2.5ms,...

23 August 2023 1,962 2 View

How to calculate the optimum annealing temperature for PCR?

15 August 2023 2,205 5 View

Since carbohydrates and lipids are macromolecules, why did no one think in the past that one of them was the genetic material?

Why was it believed in the past that the genetic material was either DNA or protein? why did no one think that carbohydrates or lipids were the genetic material? Why all the research and theories...

18 July 2023 7,177 1 View

Why do supercapacitors sometimes struggle to reach the voltage cutoff at low current densities?

Any solid reference to why sometimes, especially at very low current densities, it takes too long to reach the charging voltage cutoff, while discharge takes place much faster?

03 July 2023 5,583 3 View

Any one interesting to join our Food Molecules Interaction BOOK??

Dr. Khalifa, Prof. Zou, and Prof. Soottawat in collaboration with Elsevier Publisher warmly welcomed all professional scientists to join us in this book proposal to write and/or suggest one...

21 May 2023 2,978 0 View

Is there a problem with my RNA pellet?

Hello, I am currently having problems with RNA extraction. I am using mouse liver (C57BL6J), and I have extracted RNA from mouse liver before. Before this experiment, my final RNA pellets were...

11 August 2024 7,082 3 View

Mouse CD3 antibody sequence?

Can anyone share any reference that gives mouse specific CD3 antibody sequence. I have been searching for this since few days and no luck. Thank you very much

08 August 2024 9,157 4 View

How do I conformally do PR spin coating on trench structure?

I did PR spin coating on trench structure. I used AZ P4620 PR and the thickness or PR is around 11um. The substrate is Si. And my trench structure depth is 141um(negative way). Even though I...

08 August 2024 2,298 0 View

Can I multiplex a mouse monoclonal and rat primary for IHC (mouse brain tissue)?

Hi all, I was just wondering if anyone has experience with multiplexing a mouse monoclonal primary and a rat primary. I'm trying to multiplex by incubating them in the same well but was told by a...

06 August 2024 9,710 1 View

How much total RNA concentration to be extracted from sorted plasma cells from bone marrow of C57BL/6 mice for RT-PCR ?

i have sorted anti-NP specific plasma cells from bone marrow of C57BL/6 mice at certain times after immunization with variable counts and isolated total RNA using TRIZOL method for RT-PCR using...

05 August 2024 8,835 1 View

How to isolate lymphocytes from mouse spleen?

I have tried several times to isolate lymphocytes from mouse spleen, but all attempts have been unsuccessful. I tried most available protocols. I used different dissociation media (HBSS with Ca...

04 August 2024 9,913 7 View

In what part of the brain´s rabbit bdnf is located and include references please?

I´ve been unable to find specific information about this neurotrophin in the CNS of rabbits exclusively. There is extensive info in mice, fish and rats, but in brain´s rabbit is hard to find....

04 August 2024 762 1 View

How can I find access to heavy metal reference doses from the EPA and WHO websites?

Reference dose and Maximum acceptable concentrations HMs

03 August 2024 8,230 4 View

What can be the minimum number of animals (rats) to be used for a pilot/preliminary study on intradermal drug delivery?

Dear All I would like to know the minimum number of animals (rats) to be studied for a pilot/preliminary research on intradermal drug delivery. Can I proceed with 1 animal per group for a pilot work?

02 August 2024 4,570 1 View

How to convert g/kg Humic acid dose to kg/ha?

I used humic acid at 0.044 g/kg soil in my pot experiment. But finally, I have to recommend kg/ha. Each pot's soil weight was 11 kg. What is the solution?

02 August 2024 7,186 6 View

Rajan Tiwari

Dose are given according to the body weight, you may keep the concentration same.

Rajasekhar Eeda

Generally the dose for mice will be higher compare to rats based on body surface area.

The above statement is for small molecules like drugs, it may vary as per your study design.

Muneeb Faiq

I think Dr. Tiwari is right. IT will depend on the body weight. And by that standard, rats will go with higher amount. Concentration, however, can remain the same.

I don't think surface area has any significant role to play.