What program can I use to caclulate dipole moment efficiently and without the need of excessive computation?

Hi, I am a third year chemistry undergrad doing my group project in which I need to predict the HPLC retention time of 20 aromatic molecules. to do this we require the chemical properties of these...

24 February 2021 1,384 3 View

Do you kow of any database containing data on retention time, log P and polarizability for a large number of molecules?

Hi, I am a chemistry undergraduate doing my dissertation project on HPLC. In my project, I need to predict the HPLC retention time of 20 aromatic molecules, the calibration set. To do this I will...

24 February 2021 2,602 1 View

After SARS-CoV-2 has lost its envelope, e.g. due to surfactant disinfectants, could the RNA alone be a infectious agent for COVID-19?

Although surfactant disinfectants are generally considered to have virucidal activity against all lipid enveloped viruses, some authors claim their inefficiency against SARS-CoV-2 (as it happens...

13 July 2020 7,389 4 View

Could the end of the spread of COVID-19 be determined by environmental factors?

Beyond temperature and humidity, are there other parameters that can explain the winter spread of COVID-19? I would like to know the various opinions and scientific evidence on this intriguing issue.

27 May 2020 3,357 13 View

Could the search for a pandemic culprit lead to conflicts or new Cold Wars among Countries?

I'd like to share opinions and evidence on the following topic: Is the search for a culprit of the COVID-19 pandemic, assuming that it is an investigation with a reliably achievable result, a...

22 May 2020 5,803 8 View

Lentivirus particle production - Where's the integrase?

Hi everyone, I am facing a technical question about lentivirus production. I am going to use a 2nd generation system, in particular the widely used psPAX2 and pMD2.G. My doubt is about the...

24 March 2020 3,395 3 View

How to determine dCas9 (Nickase) cut efficiency?

I was wondering if there is any quick tool to quantify the cut efficiency of a nickase strategy. I was thinking about TIDE, querying it using either gRNA. Would you think this is a meaningful...

22 July 2019 3,306 1 View

Using powders to characterize the crystalline phase of a thin film?

I made some Metal Oxides thin films by spin coating a solgel solution on a substrate but don't have grazing incidence XRD at my disposal. Is it reasonable to dry the gel solution, treat it...

06 December 2018 8,230 3 View

Has anyone ever used Liwc (Linguistic Inquiry and Word Count) for the analysis of chat?

Http://www.liwc.net

13 April 2014 5,566 3 View

What do you imagine the colour of an ellipse to be?

We have many colors in our minds and in our eyes. Some of them are more architectural than others. An ellipse is an historical architectural figure, frequently colored.

25 November 2013 8,196 3 View

How climate change will influences human and animal behavioral change?

The role of climate change influencing the human behavior as well as economics interest

01 June 2021 0 0 View

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02 March 2021 3,060 3 View

What are the countries most affected by extreme rainfall as a result of climate change?

Increased heat, drought and insect outbreaks, all associated to climate change, have increased wildfires. Decreasing water supplies, declined agricultural yields, health impacts in cities owing to...

01 March 2021 7,168 9 View

What are the harmful effects of these extreme rainfall on the health of newborns? What are the reasons for that?

Extreme rainfall associated with climate change is causing harm to babies in some of the most forgotten places.

01 March 2021 5,647 4 View

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28 February 2021 9,936 2 View

How to arrange coordinates and extract climate dataset out of MPI-ESM-MR netcdf files?

Have a nice day everyone, I'm stuck in extracting datasets out of MPI-ESM-MR netcdf files because the latitude ranges from -3*10^6 to 3*10^6 and longitude ranges -5,9*10^6 to 5,9*10^6. Plus, the...

28 February 2021 912 3 View

When is it unnecessary to change organisational culture?

As a former management practitioner, I recall a generally accepted view that changing organisational culture is difficult, so you should only attempt it if the organisational change that you are...

27 February 2021 2,595 8 View

Does RNAiMAX transfection reagent work in serum free medium?

I diluted siRNA and RNAiMAX in opti-MEM and added to the cells which they were in the growth medium. Is it a right way? or should I culture cells in the opti-MEM medium for a while and not in...

26 February 2021 10,041 3 View

What is the best surface to culture cells isolated from a skin biopsy?

Hello, recently I am having some difficulties with maintaining the cell culture of primary cells isolated from a skin biopsy (normal and malignant). The coating of culture plates with Matrigel (a...

26 February 2021 6,151 2 View

Unknown debris sheets observed in cell culture flasks?

Hi, We culture neural progenitor cells in T175 culture flasks coated with PLO-Laminin. We have successfully grown these cells with our protocol for months. Recently, we observed large sheets...

25 February 2021 3,443 4 View