Dear Atif Suhail PVP (polyvinylpyrrolidone) as a water-soluble polymer which as a solid material is even hygroscopic. As such it dissolves not only in water but also in polar organic solvents such as ethanol, chlorinated hydrocarbons (chloroform, dichloroethylene, and DCM), N-methylpyrrolidone, dimethylformamide (DMF) and dimethyl acetamide (DMAC). To the best of my knowledge the solubility of PVP in non-polar solvents such as n-hexane and toluene is low, if not negligible. In order to get an immediate answer to your question you can easily try a few quick solubility experiments. Just place a few milligram of PVP in small vials and add a few milliliters of n-hexane and toluene. Shake briefly and observe if the material dissolves or not.
Good luck with your work and best wishes, Frank Edelmann
No. PVP K-30 polymer is also freely soluble in many organic solvents, including alcohols, some chlorinated compounds such as chloroform, methylene chloride and ethylene dichloride, nitroparans, and amines. It is essentially insoluble in hydrocarbons, ethers, some chlorinated hydrocarbons, ketones and esters.
I am sure it won't dissolve in saturated hydrocarbons or even unsaturated and halogenated aromatic solvents. Almost as good solvent as DMF and Dimethylacetamide IS DMSO (dimethyl-sulfoxide). If you feel some weird taste in your mouth, it is because DMSO already touched your skin. Not dangerous though. The Pyridine-N-oxyde is a waxy "stuff" used as H-bond acceptor, it is very soluble in H2O. PyridineN-O is a product excreted by us in the urine, but don't go drink it.
Article Predicting Poly(vinyl pyrrolidone)'s Solubility Parameter an...
Are you allowed to dilute DMSO (or pyridine) in toluene? DMSO can dissolve almost everything. However, it does coordinate metal oxides.
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