hello, i would just like to know, please, if the measurement of the oxidative stress parameters (SOD, GPx...etc) is necessary or it can give any useful information, in a protocol of the adjustment of cutaneous cancer induction by DMBA / croton oil in which, we use only different doses and frequencies of DMBA in lots of mice (topical application)? knowing that after 4 months of treatment, lots with different degrees of cancer should be obtained
Thank you
Its not necassary, but measurement of oxidative stress will give some information regarding mechanism of dmba induced toxicity and role of anti oxidant in cancer.
On theoretical basis no one can give you a precise answer to your question. We usually ask an question & the answer will be by doing research & its results will provide us with the answer>
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