When I use this eluent , the top layer of silica gel converted to gel state.
Dear Mosa:
Formic acid reacts with the silica gel. It forms a salt. This is undesirable. Clog holes. Reduced surface area silica. The eluent is adjusted for leachables. Use the recommended eluent.
Best regards.
Dear Dr. Yuri Mirgorod, instead of using Formic acid, the another alternative is acetic acid? However, acetic acid seems to have a very strong smell and must use in the fume hood if I'm not mistaken? Is there any other alternative of additive since my compound form tailing if I don't add 1% formic acid to the solvent system?
In European countries, acetic acid is added to salads, but it also forms salt. Try adding palmitic or stearic acid or acids derived from coconut oil.
Thanks Dr. Yuri, I see, other acids still form salts if used with silica but it's better to use as the compound will form tailing if I don't use acids as additives?
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