I am working on simple Y maze these days. I observed that most of my disease mice didn't show any spontaneous alteration in the experiment? However, some of the mice show some alteration. Could anyone suggest how to represent these data. because when I combined them together data has high SD.
Hello, did you confirm the setting (light, apparatus like arm length...) of spontaneous Y maze are ok by wild-type mice? (Wild-type mice should show high alternation, usually 70-80%.) Then, regarding the low spontaneous alternation, what about the frequency of arm entry in you disease mice? If too low, maybe because they are anxious or motor dysfunction (?) or hypoactivity, which will make the conclusion unconvincing; if too much entry, are they hyperactivity and possibly severe cognition problem？Only after you confirm the mentioned two points can you integrate the data.
- Badges
- Science topic
- Similar topics
- Biological Science
- Molecular Biology
- Molecular Methods
- Cloning