I have come across publications where the intending author(s) have used the term oral administration in one section (abstract) and then detailing it in the body of the manuscript as to be a gastric gavage method in actual (in the materials and methods section). The question is how legitimate would it be to hypothesize the equivalence of effects of a compound (say a herbal drug/extract) in rat administered via oral route (starting from the buccal cavity) Vs that by bypassed gastric gavage regimen?
Dear Gaurav,
you are right the oral and gastric gavage may change the effect of compounds.. I dont know why they used this term synonymously..
Oral (gastric) gavage allows more precise measurement of dosage but is also very stressful and can induce seizures in susceptible mice.
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