in CVVHDF there is dialysate so the risk of electrolyte imbalance is lower also due to convection in this modality it can pass the inflamatory madiators produced by sepsis condition .
some CRRT machines have no CVVHDF modality . instead they have CVVHFD .
CVVHFD is continues veno venus high flux dialysis it is similar to CVVHD but the dialyzer is high flux .
The optimal mode for RRT in intensive care depends on the patient and the problem. If the patient is fluid overloaded and you want to remove excess water, than the modality is some sort of ultrafiltration like CVVHF, again it the problem is to filter macromolecules convection is the answer as happens in CVVHF. But if you want to filter micro molecules or correct acid base status than you would perform CVVHDF or CVVHD.
Effectively, optimal mode for RRT depends on the patients and the pathology. We have many possibilities: SCUF, CVVHDF and CVVHF... Most of the ICU patients present an acute tubular necrosis at the origin of AKI. The simplest and the most educational mode is the mode CVVHF continues for the management of this patients.
I agree with Yalim Dikmen and Philippe Mateu that renal replacement therapy in intensive care should be individualized. In cases of hypercatabolic renal failure e.g. it may be necessary to additionly perform conventionel hemodialyses
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