Is there a way to batch-convert mass spectrometry cdf files to mzML files?

I have a set of roughly one hundred cdf files from a mass spectrometry experiment. I would like to analyse them using MetaboAnalystR, which requires mzML files as input. I know I can convert each...

28 March 2020 1,794 6 View

What is the best methodology for working with temporal data holes and deep neural networking?

Any data science and/or remote sensing experts have any insight pertaining to multivariate regression and deep neural networking with large feature set inputs and variable temporal data holes...

03 February 2020 5,246 2 View

Why are surrogates only added at the time of extraction, not at the time of sample collection and processing?

I am working on a study on pharmaceutical fate and uptake in plants. We are wondering about analyte degradation during the initial transport, processing, and storage of the soil and plant samples,...

30 October 2019 3,540 1 View

Is there a method or reference that shows how (or what is) the oxygen transmission rate (OTR) of water?

I have found multiple references on solubility however I can find nothing on transmissibility. The later is usually reserved for polymer films but in theory it should be determinable for water as...

05 August 2019 4,776 3 View

How is depth information encoded in the frequency of spectral interferograms obtained by Spectral domain optical coherence tomography?

I am trying to understand how the depth information in SD-OCT A-scans is obtained over distances far in excess of the source coherence length. From what I have gathered so far, it seems that the...

10 June 2019 6,783 2 View

How can I improve laser penetration on a confocal microscope in aortic tissue?

I am currently doing an experiment to image thick (~100 micron) cut pieces of aorta and am having a few problems. To imagine the shape of my tissue, I am cutting rings or bands of aorta and...

01 August 2018 920 3 View

Can BLAST perfrom a search including IUPAC ambiguity codes?

23 June 2017 8,927 3 View

What is the expected number of connected components in an Erdos-Renyi graph?

Let G(N,p) be an Erdos-Renyi graph, where N is the number of vertices, and p is the probability that two distinct vertices form an edge. If I plot 1-b0/N over log(p), then I obtain a curve which...

23 November 2016 6,443 3 View

Database of reagent off-target effects?

I remember seeing a recent website/database that listed commonly used cell culture and research chemical agents and their known off-target effects. Can anyone help me re-discover the site?

17 April 2016 5,311 2 View

How to conduct measured path analysis using Lisrel?

I am trying to understand how to use Lisrel to produce the best model for my survey data. I have read through the guides provided by the website but still do not seem to understand the...

19 February 2015 3,277 5 View

How to compare two groups with only two measurements?

Hiiiii everyone! I have an enquiry on statistical analysis. I was looking for many forum and it's still cannot solve my problem. I want to compare means of two groups of data but only with two...

03 March 2021 8,796 3 View

Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence?

I am on the lookout for the Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence. Does anyone know where I can find it? Thank you in advance

03 March 2021 3,568 1 View

What kind of fluid could I use for a pitfall trap that also does not invalidate molecular testing?

Hi, I want to start testing pitfall trap to obtain ants samples, but I need to conduct molecular analysis on those insects. So, what kind of fluid can I use? Ethanol expires too early and I need...

03 March 2021 5,978 5 View

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10?

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10? Since, the growth curve from day 2 to 10 won't be like the "Logistic curve" it might not follow logistic...

03 March 2021 1,401 3 View

Do we need to write protocol for a second study of a systematic review that has been registered and published?

I have conducted and published a systematic review and meta-analysis research with the topic related to public health and health pomotion (protocol was registed in PROSPERO). Now we want to...

03 March 2021 8,920 3 View

How to increase a model accuracy ?

dear community, my model is based feature extraction from non stationary signals using discrete Wavelet Transform and then using statistical features then machine learning classifiers in order to...

03 March 2021 6,994 5 View

Do I need to do linear regression before running mediation analysis using PROCESS MACRO by Hayes ?

I just wanted to check if I need to run a linear regression separately if I am using PROCESS MACRO to run mediation analysis. Thank you.

02 March 2021 4,359 3 View

Sample dilution for quantitative analysis using ELISA?

If the detection range is in ng/ml but the reference range is in ug/ml for a molecule or protein in serum or plasma .how to dilute and what is the initial volume to be taken for quantitative analysis

02 March 2021 7,670 3 View

Is There Any Feasible Method To Test Fluorescent Compounds Other Than Fluorescence Spectrometers ??

Is There Any Feasible Method To Test The Efficiency Of Fluorescent Compounds Other Than UV Spectrometers ? Suggestions Would Be Appreciated !

02 March 2021 5,785 3 View

How to calculate average trend in maximum annual NDVI from MODIS?

I am wanting to calculate the average trend in maximum annual NDVI in Iceland from 2010-2020 using MODIS MYD13Q1 V6. How would I do this? I have currently inserted the NDVI bands from the MODIS...

02 March 2021 752 2 View