I am looking for research on nutritional absorption in the GI tract and how this may interact with chronic illnesses such as IBD or autoimmune disorders. Specifically if there are any engineering models of nutritional absorption or any data sets that could use some engineering analysis.
why wont you use a model based on the nutritional requirements in those diseases?
See this paper:
Gretchen J. Mahler, Mandy B. Esch, Elad Tako, Teresa L. Southard, Shivaun D. Archer, Raymond P. Glahn and Michael L. Shuler. Oral exposure to polystyrene nanoparticles affects iron absorption. Nature Nanotechnology (2012). 12;7(4):264-71. doi:10.1038/nnano.2012.3.
Thanks Elad! That is a very interesting paper, especially the in vitro model.
Greg, Yes I am looking for a mathematical physiological model that incorporates kinetics if any such model exists yet. Simply net absorption would be very useful as well. Thanks.
Hi Andy,
For the mathemathical side I cannot help you personally, but I know that experts on both practical in-vitro as well as theorethical approaches work within TNO Zeist.
You could take a look at their web page and then look further for the mathematical approach, see http://www.tnotriskelion.com/food-feed/tim-in-vitro-dynamic-gastrointestinal-models
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