It is possible to find a patient with a deficit total or partial of LCAT, holding a concentration of HDLC in the order of 20-30 mg/dl?
Please find enclosed a paper describing a family in Majorca displaying very low concentration of HDL-C in plasma.
Here it is the previously mentioned publication. The LCAT activity in the HDL was found impaired in the mutant apoA-I-containing HDL.
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