Is anyone familiar with a bioassay to test treatment for depression?

Bat Chen R Avraham Lubin @Bat-Chen-Avraham-Lubin

15 March 2015 1 10K Report

We are looking for a cell based assay to test different drugs for treating depression, before going to the mice model.

Any ideas? We would love to learn.

Thanks in advance.

S. Béatrice Marianne Ewalds-Kvist

Look if it gives you any idea?

Front Neurosci. 2015 Jan 14;8:457.

Lithium-induced neuroprotection is associated with epigenetic modification of specific BDNF gene promoter and altered expression of apoptotic-regulatory proteins.

Dwivedi T, Zhang H1.

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